En gruppe lidelser og tilstander i hjernen som kan forårsake funksjonsforstyrrelser som karakteriseres av ulike former av anfall, enten med eller uten innvirkning på bevisstheten, og med eller uten krampeanfall.

Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.

Check Intently (1)istradefylline will enhance the degree or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

It's also helpful for individuals whose Work require them to be alert and Energetic at night when their circadian clocks are telling them to snooze.

Nedsatt konsentrasjon av ciklosporin (fifty % i en kasuistikk; ingen details foreligger fra mer sytematiske studier)

Small (one)modafinil will raise the stage or effect of lansoprazole by influencing hepatic enzyme CYP2C19 metabolism. Minor/Importance Not known. Web impact on pantoprazole actions unfamiliar due to opposing consequences of CYP450 enzymes; check

Stone et al (2002) also documented the consequences of stress on modafinil’s stimulation of enhanced gross movement in Reside rats, a few of whom have been pretreated with corticosterone or dexamethasone. They observed that worry diminished General gross motion, an effect attenuated by corticosterone pre-remedy, and strain also reduced the modafinil induced Raise in gross movement.

Mye tyder på at Modafinil gjenoppretter og/eller øker våkenhet og psychological fokus ved å forsterke alfa1 adrenerg aktivitet spesifikt i den delen av hjernen som har med søvn og oppmerksomhet.

Modafinil could potentially cause skin reactions Which might be extreme sufficient to need cure inside of a medical center. Prevent having this drugs get more info and have emergency medical assist if you have:

Modafinil is understood to possess fewer or no adverse results than These present in conventional psychostimulants for instance amphetamine, methylphenidate or copyright. It may be used as an anti-psychotic or anti-tiredness agent.

Dose changes of those drugs together with other medicine that are substrates for CYP2C19 can be necessary if modafinil is coadministered

cannabidiol will boost the stage or outcome of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Closely. Take into account decreasing the dose of sensitive CYP2C19 substrates, as clinically appropriate, when coadministered with cannabidiol.

It remains to be important to get plenty of slumber also to use superior slumber patterns though getting modafinil. Talk to your healthcare supplier about good sleep habits.

modafinil will enhance the level or effect of diazepam intranasal by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Solid or average CYP2C19 inhibitors may well lessen charge of diazepam elimination, therefore rising adverse reactions to diazepam.